Second Singapore woman needs liver transplant after taking diet pill

May 29, 2002 - 0:0
SINGAPORE -- A second Singapore woman was Tuesday fighting for her life with acute liver failure after taking a slimming pill, and medical staff said she could die within days if a donor is not found.

The 43-year-old woman, identified only as Miss Raja, had been taking "Slim 10", the same drug linked to the liver failure of Singapore television personality Andrea de Cruz.

The product was yanked from the shelves early last month when initial reports of adverse reactions emerged, but it was not until doctors reported more serious side effects two weeks later than a public warning was issued.

The health sciences authority has logged at least 13 cases of serious illness among women who had taken Slim 10, including two of acute liver failure and several of hyperthyroidism, which brings on vomiting and profuse perspiration.

De Cruz, and her actor boyfriend Pierre PNG who donated half his liver to save her life, were discharged from hospital last week and refused to discuss the link to the herbal diet pill Slim 10.

"I would like to put the whole slimming pill issue behind me, so if you don't mind I would not like to discuss it right now," the 27-year-old De Cruz said.

However, her doctor K.C. Tan blamed her liver failure on drug poisoning from Slim 10.

"Within that drug there's a banned substance called Fenfluramine which itself can cause liver damage and we suspect that's what exactly caused the damage in Andrea's liver," AFP quoted Tan as telling reporters.

Miss Raja's doctors said she took Slim 10 between January and March this year and was admitted to hospital on May 9, **** The Straits Times **** reported.

Her sister Sharlin said the family had found "a few bottles, empty bottles" of the slimming drug in a cupboard in Miss Raja's home.

Channel Newsasia said doctors have given the logistics executive "just days to a week" to live.

Efforts to find a suitable donor for Miss Raja have so far been unsuccessful but a spokeswoman at the National University Hospital (NUH) told AFP there had been several inquiries since details of the case became public.

There are 20 people waiting for a liver transplant in Singapore, with Miss Raja moved to the top of the list.

Miss Raja's family have been screened but found unsuitable for a liver transplant, and their approaches to brain-dead patients in hospitals here have all been rejected.

According to NUH about 68 percent of Singapore families say no to organ transplants, even if a dead relative has pledged his organs.